Veins, pulmonary granulomas, allergic reactions, local tissue embolism and necrosis, among which pyrogen-like reactions are common. The main sources of particulate pollution in infusion are dispensing equipment, dispensing process and air pollution. The traditional dispensing process requires a syringe as the intermediate carrier. After multiple back and forth punctures of the bottle stopper, the needle is exposed to the air multiple times. This is not only time-consuming, laborious and increases the labor intensity of nurses, but also easily contaminates the medicinal solution.
The dosage of most drugs is very close to the toxic dosage, and some even have no obvious boundaries. Especially for cyclophosphamide, operators can be affected by low-dose drugs through skin contact, respiratory inhalation, etc. during the preparation process, which has potential risks such as carcinogenesis, teratogenesis, and organ damage. There are also research results showing that methotrexate, cyclophosphamide, 5-fluorouracil and platinum can be detected in the urine of nurses with occupational exposure to drugs using biological detection methods.
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